Scientific publications
A good overview and discussion of the studies on Ivermectin can be found in the report of the FLCCC. View ->
Peer-reviewed publications
Alam, M. T. et al. Ivermectin as Pre-exposure Prophylaxis for COVID-19 among Healthcare Providers in a Selected Tertiary Hospital in Dhaka – An Observational Study. European Journal of Medical & Health Sciences, 2020; vol. 2 (6)
Alam, M.T. et al. A Case Series of 100 COVID-19 Positive Patients Treated with Combination of Ivermectin and Doxycycline. Journal of Bangladesh College of Physicians and Surgeons, 2020; vol. 38: p.10-15
Al-Kuraishy, H. et al. Is ivermectin–Azithromycin combination the next step for COVID-19?. Biomed Biotechnol Res J, 2020; vol. 4: S1:101-3
Azam, N. Some home remedies used for treatment of COVID-19 in Bangladesh. Journal of Medicinal Plant Studies. 2020; vol. 8(4): p.27-32
Bernigaud, C. et al. Bénéfice de l’ivermectine: de la gale à la COVID-19, un exemple de sérendipité. Annales de Dermatologie et de Vénéréologie, 2020; vol. 147 (12): A194
Caly, L. et al. The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro. Antiviral Research, 2020; vol. 178 (June)
Camprubi, D. et al. Lack of efficacy of standard doses of ivermectin in severe COVID-19 patients. PLoS ONE, 2020; vol. 15 (11)
Carvallo, H. Study of the Efficacy and Safety of Topical Ivermectin Iota-Carrageenan in the Prophylaxis against COVID-19 in Health Personnel. Journal of Biomedical Research and Clinical Investigation, 2020; vol. 2 (1)
Chacar, A. et al. Effectiveness of Ivermectin in SARS-CoV-2/COVID-19 Patients. Internation Journal of Sciences, 2020; vol. 9 (September): p.31-35
Espitia-Hernandez, G. Effects of Ivermectin-azithromycin-cholecalciferol combined therapy on COVID-19 infected patients: A proof of concept study. Biomedical Research: An International Journal of Medical Sciences, 2020; vol. 31 (5)
Fonseca, S. et al. Risk of hospitalization for Covid-19 outpatients treated with various drug regimens in Brazil: Comparative analysis. Travel Medicine and Infectious Diseases, 2020; vol.38
Guerrero, E. et al. COVID-19: The Ivermectin African Enigma. Damage Control Surgery (I), 2020; vol. 51(4)
Guzzo, C. et al. Safety, Tolerability, and Pharmacokinetics of Escalating High Doses of Ivermectin in Healthy Adult Subjects. Journal of Clinical Pharmacology, 2002; vol. 42(10): p.1122-1133
Heidary, F. & R. Gharebaghi, Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen. The Journal of Antibiotics, 2020; vol. 73: p. 593-602
Hellwig, M. & A. Maya A COVID-19 prophylaxis? Lower incidence associated with prophylactic administration of ivermectin. International Journal of Antimicrobial Agents, 2020; November
Hussain, S. Outcome of ivermectin and doxycycline in cancer patients with COVID-19: A positive experience in Bangladesh. International Journal of Molecular and Immuno Oncology, 2020; December
Jans, D. & K. Wagstaff Ivermectin as a Broad-Spectrum Host-Directed Antiviral: The Real Deal? Cells, 2020; vol. 9(9)
Kahn, S. et al. Ivermectin for COVID-19: A broad-spectrum veterinary endectocide with antiviral activity. Journal of Food and Animal Sciences, 2020; vol. 1(1): p.1-6
Kaur, H. Ivermectin as a potential drug for treatment of COVID-19: an in-sync review with clinical and computational attributes. Pharmacological Reports, 2021
Kory, P. et al. Review of .the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19. Frontiers in Pharmocology, 2020
Lehrer, S. & P. Rheinstein Ivermectin Docks to the SARS-CoV-2 Spike Receptor-binding Domain Attached to ACE2. In Vivo, 2020; vol. 34(5): p. 3023-3026
Li, N. et al. Quantitative proteomics reveals a broad‐spectrum antiviral property of ivermectin, benefiting for COVID‐19 treatment. Journal of Cellular Physiology, 2020; p.1-17
Madrid, R. et al. Safety of oral administration of high doses of ivermectin by means of biocompatible polyelectrolytes formulation. Heliyon, 2021; vol. 7(1)
McCullough, P. et al. Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19). Reviews in Cardiovascular Medicine, 2020; vol 21 (4): p.517-530
Mittal, N & R. Mittal. Inhaled route and anti-inflammatory action of ivermectin: Do they hold promise in fighting against COVID-19? Medical Hypotheses, 2020; November
Momekov, G. & D. Momekova Ivermectin as a potential COVID-19 treatment from the pharmacokinetic point of view: antiviral levels are not likely attainable with known dosing regimens. Biotechnology & Biotechnological Equipment, 2020; vol. 34 (1)
Mody, V. et al. Identification of 3-chymotrypsin like protease (3CLPro) inhibitors as potential anti-SARS-CoV-2 agents. Communications Biology, 2021; 4: art. 93
Navarro, M. et al. Safety of high-dose ivermectin: a systematic review and meta-analysis. Journal of Antimicrobial Chemotherapy, 2020; vol. 75(4): p.827-834
Núñez, A. et al. Therapeutic Efficacy of Ivermectin as an Adjuvant in the Treatment of Patients with COVID-19 Study conducted at the Social Security Institute for Workers of the State of Chiapas, ISSTECH, Mexico. International Journal of Innovative Science and Research Technology, 2020; vol. 5(7): p.211-215
Padhy, B. et al. Therapeutic potential of ivermectin as add on treatment in COVID 19: A systematic review and meta-analysis. Journal of Pharmacy and Pharmaceutical Sciences, 2020; 23: p.462-469
Procter, B. et al. Clinical outcomes after early ambulatory multidrug therapy for high-risk SARS-CoV-2 (COVID-19) infection. Reviews in Cardiovascular Medicine, 2020; vol. 21 (4): p. 611-614
Podder, C.S. Outcome of ivermectin treated mild to moderate COVID-19 cases: a single-centre, open-label, randomised controlled study. I.M.C. Journal of Medical Science, 2020; vol. 14 (2)Rajter, J. et al. Use of Ivermectin Is Associated With Lower Mortality in Hospitalized Patients With Coronavirus Disease 2019: The ICON Study. CHEST, 2020; october
Schmith, V. et al. The Approved Dose of Ivermectin Alone is not the Ideal Dose for the Treatment of COVID-19. Clin. Pharmocol Ther., 2020; May
Shouman, W. Use of Ivermectin as a potential chemoprophylaxis for COVID-19 in Egypt : A Randomised clinical trial. Journal of Clinical and Diagnostic Research, 2020
Spoorthi, V & Sasank S. Utility of Ivermectin and Doxycycline combination for the treatment of SARS-CoV-2. IAIM, 2020; vol. 7(10): p.177-182.
Surnar, B. Clinically Approved Antiviral Drug in an Orally Administrable Nanoparticle for COVID-19. ACS Pharmalogical & Translational Science, 2020; December
Preprint studies
Afsar, N. Ivermectin Use Associated with Reduced Duration of COVID-19 Febrile Illness in a Community Setting
Aguirre-Chang, G. et al. Post-Acute or Prolonged COVID-19 Treatment with Ivermectin for Patients with Persistent, or Post-Acute Symptoms
Aguirre-Chang, G. & A. Figueredo, COVID-19: Pre-exposure Prophylaxis with Ivermectin for exposed people.
Aguirre-Chang, G. et al. COVID-19 Persistent: Treatment with Ivermectin and Acetylsalicylic acid of patients with the persistent syndrome of anosmia or hyposmia
Babalola, O. et al. Ivermectin shows clinical benefits in mild to moderate Covid19 disease: A randomised controlled double blind dose response study in Lagos.
Behera, P. et al. Role of ivermectin in the prevention of COVID-19 infection among healthcare workers in India: A matched case-control study.
Budhiraja, S. et al. Clinical Profile of First 1000 COVID-19 Cases Admitted at Tertiary Care Hospitals and the Correlates of their Mortality: An Indian Experience
Bukhari, K. et al. Efficacy of Ivermectin in COVID-19 Patients with Mild to Moderate Disease
Cadegiani, F. A. Early COVID-19 Therapy with Azithromycin Plus Nitazoxanide, Ivermectin or Hydroxychloroquine in Outpatient Settings Significantly Reduced Symptoms Compared to Known Outcomes in Untreated Patients
Carvallo, H. Safety and Efficacy of the combined use of ivermectin, dexamethasone, enoxaparin and aspirin against COVID-19.
Chamie-Quintero, J. et al. Sharp Reductions in COVID-19 Case Fatalities and Excess Deaths in Peru in Close Time Conjunction, State-By-State, with Ivermectin Treatments
Cobos-Campos, R. et al. Potential use of ivermectin for the treatment and profilaxis of SARS-CoV-2 infection: Efficacy of ivermectin for SARS-CoV-2
Dias de Melo, G. Anti-COVID-19 efficacy of ivermectin in the golden hamster
Elgazzer, A. et al. Efficacy and Safety of Ivermectin for Treatment and prophylaxis of COVID-19 Pandemic
Frances-Monerris, A. et al. Has Ivermectin Virus-Directed Effects against SARS-CoV-2? Rationalizing the Action of a Potential Multitarget Antiviral Agent
Gorial, F.I. et al. Effectiveness of Ivermectin as add-on Therapy in COVID-19 Management (Pilot Trial)
Hashim, H.A. et al. Controlled randomized clinical trial on using Ivermectin with Doxycycline for treating COVID-19 patients in Baghdad, Iraq
Hill, A. et al. Meta-analysis of randomized trials of ivermectin to treat SARS-CoV-2 infection
Jeffreys, L. et al. Remdesivir-Ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2
Kalfas, S. et al. The Therapeutic Potential of Ivermectin for COVID-19: a systematic review of Mechanisms and Evididence.
Kirty, R. et al. Ivermectin as a potential treatment for mild to moderate COVID-19: A double blind randomized placebo-controlled trial
Krolewiecki, A. et al. Antiviral Effect of High-Dose Ivermectin in Adults with COVID-19: A Pilot Randomised, Controlled, Open Label, Multicentre Trial
Lawrie, T. Ivermectin reduces the risk of death from COVID-19 -a rapid review and meta-analysis in support of the recommendation of the Front Line COVID-19 Critical Care Alliance.
Mohan, A. et al. Ivermectin in mild and moderate COVID-19 (RIVET-COV): a randomized, placebo-controlled trial.
Morgenstern, J. et al. The use of compassionate Ivermectin in the management of symptomatic outpatients and hospitalized patients with clinical diagnosis of COVID-19 at the Medical Center Bournigal and the Medical Center Punta Cana, Rescue Group, Dominican Republic, from may 1 to august 10, 2020
Niaee, M.S. et al. Ivermectin as an adjunct treatment for hospitalized adult COVID-19 patients: A randomized multi-center clinical trial
Soto-Becarra, P. et al. Real-world effectiveness Ivermectin as Pre-exposure Prophylaxis for COVID-19 among Healthcare Providers in a Selected Tertiary Hospital in Dhaka – An Observational Studyof hydroxychloroquine, azithromycin, and ivermectin among hospitalized COVID-19 patients: results of a target trial emulation using observational data from a nationwide healthcare system in Peru
Swargiary, A. Ivermectin as a promising RNA-dependent RNA polymerase inhibitor and a therapeutic drug against SARS-CoV2: Evidence from in silico studies.
Turkia, M. FLCCC Alliance MATH ascorbic acid and I-MASK ivermectin protocols for COVID-19 – A Brief Review
Clinical Trials with Results
Chala, R. Prophylaxis Covid-19 in Healthcare Agents by Intensive Treatment With Ivermectin and Iota-carrageenan (Ivercar-Tuc). 2021
Mahmud, R, Clinical Trial of Ivermectin Plus Doxycycline for the Treatment of Confirmed Covid-19 Infection. 2020
Okomuş, N. Ivermectin for servere COVID-19 management. 2020
Raad, H. In vivo use of ivermectin (IVR) for treatment for corona virus infected patients (COVID-19): a randomized controlled trial. 2020
Shouman, W. M. Use of Ivermectin as a Prophylactic Option in Asymptomatic Family Close Contacts with Patients of COVID-19. 2020
Review article
Frediansyah, A. et al. Antivirals for COVID-19: A critical review. Clinical Epidemiology and Global Health, 2020; vol. 9: p. 90-98
Scientific Letters
Khan, S. et al. Ivermectin Treatment May Improve the Prognosis of Patients With COVID-19. Archivos de Bronconeumología, 2020; vol. 56 (12): p. 828-830
Pandey, S. et al. Ivermectin in COVID-19: What do we know? Diabetes & Metabolic Syndrome: Research & Reviews, 2020; vol. 14 (6): p. 1921-1922
Letter to the editor
Gupta, D. et al. Ivermectin: potential candidate for the treatment of Covid 19. The Brazilian Journal of Infectious Diseases, 2020; vol. 24 (4): p. 369 -371
DiNicolantonia, J. et al. Ivermectin may be a clinically useful anti-inflammatory agent for late-stage COVID-19. Open Heart, 2020; vol. 7(4)
Pena-Silva, R. Pharmacokinetic considerations on the repurposing of ivermectin for treatment of COVID‐19. British Journal of Clinical Pharmocology. 2020
Rizzo, E. Ivermectin, Antiviral properties and COVID-19: a possible new mechanism of action. Naunyn-Schmiedeberg´s Archives of Pharmacology, 2020; July, 393 (7): p. 1153-1156.
Vora, A. et al. White paper on Ivermectin as a potential therapy for COVID-19. Indian Journal on Tuberculosis, 2020; vol. 67(3): p.448-451