Wetenschappelijke publicaties


Een goed overzicht en bespreking van de onderzoeken naar Ivermectine is in het rapport van de FLCCC te vinden. Bekijk ->

Peer-reviewed publicaties

Abd-Elsalam, S.et al. Clinical study evaluating the efficacy of ivermectin in COVID-19 treatment: A randomized controlled study. Journal of Medical Virology, 2021; vol. 93(10): p. 5833-5838

Ahmed, S. et al. A five day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness. International Journal of Infectious Diseases, 2020; December


Alam, M.T. et al. A Case Series of 100 COVID-19 Positive Patients Treated with Combination of Ivermectin and Doxycycline. Journal of Bangladesh College of Physicians and Surgeons, 2020; vol. 38: p.10-15

Al-Kuraishy, H. et al. Is ivermectin–Azithromycin combination the next step for COVID-19?. Biomed Biotechnol Res J, 2020; vol. 4: S1:101-3


Arévalo, A. et al. Ivermectin reduces in vivo coronavirus infection in a mouse experimental model. Scientific Reports, 2021; vol. 11 (7132)



Azam, N. Some home remedies used for treatment of COVID-19 in Bangladesh. Journal of Medicinal Plant Studies.
2020; vol. 8(4): p.27-32





Bernigaud, C. et al. Bénéfice de l’ivermectine: de la gale à la COVID-19, un exemple de sérendipité. Annales de Dermatologie et de Vénéréologie, 2020; vol. 147 (12): A194


Caly, L. et al. The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro. Antiviral Research, 2020; vol. 178 (June)



Carvallo, H. Study of the Efficacy and Safety of Topical Ivermectin + Iota-Carrageenan in the Prophylaxis against COVID-19 in Health Personnel. Journal of Biomedical Research and Clinical Investigation, 2020; vol. 2 (1)

Chacar, A. et al. Effectiveness of Ivermectin in SARS-CoV-2/COVID-19 Patients. Internation Journal of Sciences, 2020; vol. 9 (September): p.31-35



Chowdhury, A. et al. A Comparative Study on Ivermectin-Doxycycline and Hydroxychloroquine-Azithromycin Therapy on COVID-19 Patients. Eurasian Journal on Medicine and Oncology, 2021; vol. 5 (1): p. 63-70


Elkholy, K. et al. Ivermectin: A Closer Look at a Potential Remedy. Cureus, 2020; vol. 12 (9)


Espitia-Hernandez, G. Effects of Ivermectin-azithromycin-cholecalciferol combined therapy on COVID-19 infected patients: A proof of concept study. Biomedical Research: An International Journal of Medical Sciences, 2020; vol. 31 (5)


Faisal, R. et al. Potential use of azithromycin alone and in combination with ivermectin in fighting against the symptoms of COVID-19. Professional Medical Journal, 2021; vol. 28(5): p. 737-741




Guerrero, E. et al. COVID-19: The Ivermectin African Enigma. Damage Control Surgery (I), 2020; vol. 51(4)

Guzzo, C. et al. Safety, Tolerability, and Pharmacokinetics of Escalating High Doses of Ivermectin in Healthy Adult Subjects. Journal of Clinical Pharmacology, 2002; vol. 42(10): p.1122-1133


Heidary, F. & R. Gharebaghi, Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen. The Journal of Antibiotics, 2020; vol. 73: p. 593-602

Hellwig, M. & A. Maya A COVID-19 prophylaxis? Lower incidence associated with prophylactic administration of ivermectin. International Journal of Antimicrobial Agents, 2020; November

Hussain, S. Outcome of ivermectin and doxycycline in cancer patients with COVID-19: A positive experience in Bangladesh. International Journal of Molecular and Immuno Oncology, 2020; December





Kory, P. et al. Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19. American Journal of Therapeutics, 2021; vol. 29(3): p. e299-e318




Lehrer, S. & P. Rheinstein Ivermectin Docks to the SARS-CoV-2 Spike Receptor-binding Domain Attached to ACE2. In Vivo, 2020; vol. 34(5): p. 3023-3026





Mahmud, R. et al. Ivermectin in combination with doxycycline for treating COVID-19 symptoms: a randomized trial. Journal of International Medical Research, 2021; mei


McCullough, P. et al. Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19). Reviews in Cardiovascular Medicine, 2020; vol 21 (4): p.517-530





Navarro, M. et al. Safety of high-dose ivermectin: a systematic review and meta-analysis. Journal of Antimicrobial Chemotherapy, 2020; vol. 75(4): p.827-834

Niaee, M. et al Ivermectin as an adjunct treatment for hospitalized adult COVID-19 patients: A randomized multi-center clinical trial. Asian Pacific Journal of Tropical Medicine, 2021; vol. 14(6): p.266-273



Padhy, B. et al. Therapeutic potential of ivermectin as add on treatment in COVID 19: A systematic review and meta-analysis. Journal of Pharmacy and Pharmaceutical Sciences, 2020; 23: p.462-469

Pareja-Cruz, A. & J. Luque-Espino Seguridad y eficacia de ivermectina en tiempos de COVID-19. Horizonte Médico (Lima), 2021; vol. 21 (1): e1393



Pott-Junior, H. et al. Use of ivermectin in the treatment of Covid-19: A pilot trial. Toxicology Reports, 2021; vol. 8: p. 505-510






Shouman, W. Use of Ivermectin as a potential chemoprophylaxis for COVID-19 in Egypt : A Randomised clinical trial. Journal of Clinical and Diagnostic Research, 2021; vol. 15 (2): p. 27-32

Spoorthi, V & S. Sasank Utility of Ivermectin and Doxycycline combination for the treatment of SARS-CoV-2. IAIM, 2020; vol. 7(10): p.177-182.

Surnar, B. Clinically Approved Antiviral Drug in an Orally Administrable Nanoparticle for COVID-19. ACS Pharmalogical & Translational Science, 2020; December





Review articles

Frediansyah, A. et al. Antivirals for COVID-19: A critical review. Clinical Epidemiology and Global Health, 2020; vol. 9: p. 90-98


Formiga, F. et al. Ivermectin: an award-winning drug with expected antiviral activity against COVID-19. Journal of Controlled Release, 2021; vol. 329: p. 758-761


Hirsch, R. & H. Carvallo, Ivermectin as Prophylaxis Against COVID-19 Retrospective Cases Evaluation. Microbiol Infect Dis. 2020; vol. 4(4): p. 1-8


Jans, D. & K. Wagstaff Ivermectin as a Broad-Spectrum Host-Directed Antiviral: The Real Deal? Cells, 2020; vol. 9 (9)


Martin, A. & D. Jans Antivirals that target the host IMPα/β1-virus interface. Biochemical Society Transactions, 2021; vol. 47 (1): p. 281-295


Mohan, P. et al. Role of ivermectin in COVID-19: Wishful thinking or scientific optimism. Journal of Marine Medical Society, 2020; vol. 22 (3): p.27-31


Rakedzon, S. et al. From hydroxychloroquine to ivermectin: what are the anti-viral properties of anti-parasitic drugs to combat SARS-CoV-2? Journal of Travel Medicine, 2021; vol. 28 (2): p. 1-9


Schellack, N. et al. Ivermectin in the treatment of COVID-19— friend or foe? Professional Nursing Today, 2021; vol. 25 (1)


Wehbe, Z. et al. Repurposing Ivermectin for COVID-19: Molecular Aspects and Therapeutic Possibilities. Frontiers in Immunology. 2021; vol. 12 (663586)


Yagisawa, M. et al. Global trends in clinical studies of ivermectin in COVID-19. The Japanese Journal of Antibiotics, 2021; Vol. 74 (1): p. 44 - 95


Zaidi, A. & P. Mobaraki The mechanisms of action of ivermectin against SARS-CoV-2—an extensive review, The Journal of Antibiotics, 2021; december


Preprint studies

 

Afsar, N. Ivermectin Use Associated with Reduced Duration of COVID-19 Febrile Illness in a Community Setting


Aguirre-Chang, G. et al. Post-Acute or Prolonged COVID-19 Treatment with Ivermectin for Patients with Persistent, or Post-Acute Symptoms


Aguirre-Chang, G. & A. Figueredo, COVID-19: Pre-exposure Prophylaxis with Ivermectin for exposed people.


Aguirre-Chang, G. et al. COVID-19 Persistent: Treatment with Ivermectin and Acetylsalicylic acid of patients with the persistent syndrome of anosmia or hyposmia


Babalola, O. et al. A Randomized Controlled Trial of Ivermectin Monotherapy Versus Hydroxychloroquine, Ivermectin, and Azithromycin Combination Therapy in Covid-19 Patients in Nigeria


Behera, P. et al. Prophylactic role of ivermectin in SARS-CoV-2infection among healthcare workers


Beltran-Gonzalez, J. et al. Efficacy and safety of Ivermectin and Hydroxychloroquine in patients with severe COVID-19. A randomized controlled trial.


Biber, A. et al. Favorable outcome on viral load and culture viability using Ivermectin in early treatment of non-hospitalized patients with mild COVID-19 – A double-blind, randomized placebo-controlled trial


Budhiraja, S. et al. Clinical Profile of First 1000 COVID-19 Cases Admitted at Tertiary Care Hospitals and the Correlates of their Mortality: An Indian Experience


Bukhari, K. et al. Efficacy of Ivermectin in COVID-19 Patients with Mild to Moderate Disease


Cadegiani, F. A. Early COVID-19 Therapy with Azithromycin Plus Nitazoxanide, Ivermectin or Hydroxychloroquine in Outpatient Settings Significantly Reduced Symptoms Compared to Known Outcomes in Untreated Patients


Carvallo, H. Safety and Efficacy of the combined use of ivermectin, dexamethasone, enoxaparin and aspirin against COVID-19.


Chala, R. et al. A RANDOMIZED TRIAL - INTENSIVE TREATMENT BASED IN IVERMECTIN AND IOTA-CARRAGEENAN AS PRE-EXPOSURE PROPHYLAXIS FOR COVID- 19 IN HEALTHCARE AGENTS


Chamie-Quintero, J. et al. Sharp Reductions in COVID-19 Case Fatalities and Excess Deaths in Peru in Close Time Conjunction, State-By-State, with Ivermectin Treatments


Cobos-Campos, R. et al. Potential use of ivermectin for the treatment and profilaxis of SARS-CoV-2 infection: Efficacy of ivermectin for SARS-CoV-2


Dias de Melo, G. Anti-COVID-19 efficacy of ivermectin in the golden hamster


Elgazzer, A. et al. Efficacy and Safety of Ivermectin for Treatment and prophylaxis of COVID-19 Pandemic


Frances-Monerris, A. et al. Has Ivermectin Virus-Directed Effects against SARS-CoV-2? Rationalizing the Action of a Potential Multitarget Antiviral Agent


Gorial, F.I. et al. Effectiveness of Ivermectin as add-on Therapy in COVID-19 Management (Pilot Trial)


Hashim, H.A. et al. Controlled randomized clinical trial on using Ivermectin with Doxycycline for treating COVID-19 patients in Baghdad, Iraq


Hazan, S. et al. Effectiveness of Ivermectin-Based Multidrug Therapy in Severe Hypoxic Ambulatory COVID-19 Patients


Hill, A. et al. Meta-analysis of randomized trials of ivermectin to treat SARS-CoV-2 infection


Jeffreys, L. et al. Remdesivir-Ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2


Kalfas, S. et al. The Therapeutic Potential of Ivermectin for COVID-19: a systematic review of Mechanisms and Evididence.


Kerr, L. et al. Ivermectin prophylaxis used for COVID-19 reduces COVID-19 infection and mortality rates: A 220,517-subject, populational-level retrospective citywide observational study.


Kirty, R. et al. Ivermectin as a potential treatment for mild to moderate COVID-19: A double blind randomized placebo-controlled trial


Kumar, N. et al. Moxidectin and ivermectin inhibit SARS-CoV-2 replication in VeroE6cells but not in human primary airway epithelium cells


Lawrie, T. Ivermectin reduces the risk of death from COVID-19 -a rapid review and meta-analysis in support of the recommendation of the Front Line COVID-19 Critical Care Alliance.


Merino, J. et al. Ivermectin and the odds of hospitalization due to COVID-19: evidence from a quasi-experimental analysis based on a public intervention in Mexico City


Mohan, A. et al. Ivermectin in mild and moderate COVID-19 (RIVET-COV): a randomized, placebo-controlled trial.


Rodríguez-Gutiérrez, R. et al. Ivermectin in the Prophylaxis and Treatment of Patients with SARS-CoV-2: A Living Systematic Review and Meta-Analysis


Soto-Becarra, P. et al. Real-world effectiveness  Ivermectin as Pre-exposure Prophylaxis for COVID-19 among Healthcare Providers in a Selected Tertiary Hospital in Dhaka – An Observational Studyof hydroxychloroquine, azithromycin, and ivermectin among hospitalized COVID-19 patients: results of a target trial emulation using observational data from a nationwide healthcare system in Peru


Swargiary, A. Ivermectin as a promising RNA-dependent RNA polymerase inhibitor and a therapeutic drug against SARS-CoV2: Evidence from in silico studies.


Tanioka, H. et al. Why COVID-19 is not so spread in Africa: How does Ivermectin affect it?


Turkia, M. A Timeline of Ivermectin-Related Events in the COVID-19 Pandemic [April 3, 2021]


Turkia, M. FLCCC Alliance MATH+ ascorbic acid and I-MASK+ ivermectin protocols for COVID-19 – A Brief Review


Wiseman, D. & P. Kory Possible clustering and/or drug switching confounding obscures up to 56% reduction of symptom persistence by ivermectin. Data Summary for comment posted to JAMA re: Lopez-Medina et al.


Clinical Trials met resultaten


Scientific Letters

Khan, S. et al. Ivermectin Treatment May Improve the Prognosis of Patients With COVID-19. Archivos de Bronconeumología, 2020; vol. 56 (12): p. 828-830


Pandey, S. et al. Ivermectin in COVID-19: What do we know? Diabetes & Metabolic Syndrome: Research & Reviews, 2020; vol. 14 (6): p. 1921-1922


Letter to the editor

Gupta, D. et al. Ivermectin: potential candidate for the treatment of Covid 19. The Brazilian Journal of Infectious Diseases, 2020; vol. 24 (4): p. 369 -371


DiNicolantonia, J. et al. Ivermectin may be a clinically useful anti-inflammatory agent for late-stage COVID-19. Open Heart, 2020; vol. 7(4)


Pena-Silva, R. Pharmacokinetic considerations on the repurposing of ivermectin for treatment of COVID‐19. British Journal of Clinical Pharmocology. 2020


Rizzo, E. Ivermectin, Antiviral properties and COVID-19: a possible new mechanism of action. Naunyn-Schmiedeberg´s Archives of Pharmacology, 2020; July, 393 (7): p. 1153-1156.


Vora, A. et al. White paper on Ivermectin as a potential therapy for COVID-19. Indian Journal on Tuberculosis, 2020; vol. 67(3): p.448-451

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